The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2025

Filed:

May. 18, 2023
Applicant:

Xwpharma Ltd., Grand Cayman, KY;

Inventors:

Jia-Ning Xiang, Fremont, CA (US);

Zude Qi, Wuhan, CN;

Xianbo Liu, Wuhan, CN;

Dezheng Ning, Wuhan, CN;

Assignee:

XWPHARMA LTD., Grand Cayman, KY;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 249/00 (2006.01); A61K 9/00 (2006.01); A61K 31/4196 (2006.01); A61K 31/454 (2006.01); A61K 31/497 (2006.01); A61P 35/00 (2006.01); C07D 233/00 (2006.01); C07D 249/02 (2006.01); C07D 249/08 (2006.01); C07D 257/04 (2006.01); C07D 271/00 (2006.01); C07D 271/02 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 419/12 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 9/0053 (2013.01); C07D 249/08 (2013.01); C07D 401/12 (2013.01); C07D 419/12 (2013.01);
Abstract

Nuclear transport modulators are disclosed. The compounds can inhibit nuclear transporters such as the exportin-1 transporter. The compounds and pharmaceutical compositions comprising the compounds can be used to treat neurological diseases and cancer.


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