The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2025

Filed:

Dec. 28, 2022
Applicant:

Terran Biosciences Inc., Miami Beach, FL (US);

Inventors:

Samuel Clark, Miami Beach, FL (US);

Matthew Duncton, Las Vegas, NV (US);

Assignee:

Terran Biosciences Inc., Miami Beach, FL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 317/58 (2006.01); A61K 31/36 (2006.01); A61P 25/18 (2006.01); A61P 25/22 (2006.01);
U.S. Cl.
CPC ...
C07D 317/58 (2013.01); A61K 31/36 (2013.01); A61P 25/18 (2018.01); A61P 25/22 (2018.01); C07B 2200/13 (2013.01);
Abstract

Described herein are isotopically enriched analogs of methylone (e.g., deuterated analogs of methylone (e.g., (S)-methylone and (R)-methylone) with improved characteristics. Also described herein are salts (such as hydrochloride salt) and solid forms (e.g., crystalline forms) of methylone. Also described herein are stereoisomers (e.g., enantiomers) of methylone. The present disclosure also provides methods of making and methods of use of the methylone or methylone analogs and solid forms of 3,4-methylenedioxy-N-ethylcathinone hydrochloride described herein to treat brain and neurological disorders such as depression.


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