The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2025
Filed:
Jun. 26, 2022
3,4-dihydroxy-n-(1'-benzyl-2′-hydroxyethyl)-2-methylpyridine chloride, and synthesis and use thereof
Hangzhou Zede Pharma-tech Co. Ltd., Zhejiang, CN;
Yongping Yu, Hangzhou, CN;
Robert Charles Hider, London, GB;
Xin Yuan, Hangzhou, CN;
Feng Han, Nanjing, CN;
Wenteng Chen, Hangzhou, CN;
Guolin Zhang, Hangzhou, CN;
Zudong Liu, Hangzhou, CN;
Yu Zhang, Nanjing, CN;
HANGZHOU ZEDE PHARMA-TECH CO. LTD., Hangzhou, CN;
Abstract
The present application provides the preparation and use of a 3,4-dihydroxyl-N-(1′-benzyl-2′-hydroxyethyl)-2-methyl pyridine chloride. According to the present application, a 3,4-dihydroxyl-N-(1′-benzyl-2′-hydroxyethyl)-2-methyl pyridine chloride is directly synthesized by a one-step reaction, and the compound includes a pharmaceutically acceptable salt thereof. 3,4-dihydroxyl-N-(1′-benzyl-2′-hydroxyethyl)-2-methyl pyridine chloride has been proved to have a good antiparkinsonian activity by animal tests, and it is a class of novel antiparkinsonian drug candidates. It can be used in the preparation of drugs for the treatment of a Parkinson's disease, and its structural formula (I) is as follows: