The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2025

Filed:

Aug. 26, 2022
Applicant:

Ut-battelle, Llc, Oak Ridge, TN (US);

Inventors:

Brian Sanders, Knoxville, TN (US);

Stephanie S. Galanie, Scotch Plains, NJ (US);

Jerry M. Parks, Knoxville, TN (US);

Assignee:

UT-Battelle, LLC, Oak Ridge, TN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 243/28 (2006.01); A61P 31/14 (2006.01); C07C 255/03 (2006.01);
U.S. Cl.
CPC ...
C07C 243/28 (2013.01); A61P 31/14 (2018.01); C07C 255/03 (2013.01);
Abstract

A compound having the following structure: wherein: Ris a linker having the formula —(CH)-L-, wherein Lcontains 1-6 carbon atoms and at least one —NH— linkage and at least one oxygen-containing or sulfur-containing linkage, and n is an integer of 0-3; Ris a group having the formula —C(Y)-E, wherein Y is O or S, and E is a hydrocarbon group and either: (i) at least one carbon-carbon or carbon-nitrogen unsaturated bond or (ii) at least one alkyl halide group; Ris selected from H, NR', NHC(O)R′, and —(CH)-T, wherein T contains at least one —NH— linkage; R, R, R, R, R, and Rare independently selected from of H, hydrocarbon groups containing 1-3 carbon atoms, fluorine atom, and chlorine atom; X is N or CR, wherein Ris selected from H, hydrocarbon groups containing 1-3 carbon atoms, fluorine atom, and chlorine atom; and pharmaceutically acceptable salts thereof.


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