The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2025

Filed:

Feb. 15, 2019
Applicant:

Astrego Diagnostics Ab, Uppsala, SE;

Inventors:

Özden Baltekin, Uppsala, SE;

Ove Öhman, Uppsala, SE;

Martin Lovmar, Mölndal, SE;

Johan Elf, Uppsala, SE;

Mikael Olsson, Uppsala, SE;

Assignee:

ASTREGO DIAGNOSTICS AB, Uppsala, SE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); B01D 61/18 (2006.01); B01D 63/00 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); B01D 61/18 (2013.01); B01D 63/005 (2013.01); B01L 3/502715 (2013.01); B01L 3/502746 (2013.01); G01N 33/5008 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0652 (2013.01); B01L 2200/10 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0861 (2013.01); B01L 2400/082 (2013.01);
Abstract

A capturing of target cells from a biological sample is achieved by inducing a flow of the biological sample in a flow channel () of an upstream microfluidic device (). Target cells present in the biological sample are captured in cell channels () of the upstream microfluidic device (). Once at least a minimum number of target cells are captured in the cell channels (), the flow of the biological sample in the flow channel is reduced and are verse flow is applied at the upstream microfluidic device () to release the target cells captured in the cell channels () of the upstream microfluidic device () and enable transfer the target cells into cell channels () of a downstream microfluidic device ().


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