The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2025
Filed:
Mar. 20, 2020
Applicant:
Lonza Sales Ag, Basel, CH;
Inventors:
Aaron Noyes, Melrose, MA (US);
Michael Doherty, Somerville, MA (US);
Kimberly Ellis, Somerville, MA (US);
Raymond Bourdeau, Watertown, MA (US);
Kayla Desanty, Bedford, MA (US);
Assignee:
LONZA SALES AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 15/36 (2006.01); A61K 39/00 (2006.01); C12M 1/00 (2006.01);
U.S. Cl.
CPC ...
B01D 15/362 (2013.01); A61K 39/00 (2013.01); B01D 15/363 (2013.01); C12M 29/10 (2013.01);
Abstract
The present disclosure relates to multistep chromatographic methods for preparing extracellular vesicles (EVs). The methods were demonstrated to be effective in preparing highquality EVs in a large scale. The methods enable preparation of EVs for therapeutic and diagnostic applications, and isolation and/or sub-fractionation of EVs with desired properties for specific use.