The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2025

Filed:

Aug. 09, 2019
Applicant:

The University of Greenwich, Greenwich, GB;

Inventors:

Simon Richardson, Greenwhich, GB;

Benedita Feron, Greenwich, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 9/1271 (2025.01); A61K 9/1277 (2025.01); A61K 31/7105 (2006.01); A61K 38/46 (2006.01); A61P 31/14 (2006.01); C12N 9/12 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 9/1277 (2013.01); A61K 9/1271 (2013.01); A61K 31/7105 (2013.01); A61K 38/465 (2013.01); A61P 31/14 (2018.01); C12N 9/12 (2013.01); C12N 15/113 (2013.01); C07K 2319/00 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01);
Abstract

The invention relates to liposomes, methods of producing liposomes, and methods of loading cell-derived liposomes with cargo molecules. The invention extends to such liposomes per se, and to the use of these liposomes as cellular delivery systems for the delivery of biologically and therapeutically active payload molecules, such as small molecules, RNAi molecules (e.g. siRNA), bioactive proteins, genome editing tools (e.g. Cas9) and drugs into cells for treating a range of disorders. The liposomes may also be used in a range of diagnostic and theranostic applications. The invention extends to pharmaceutical compositions comprising such liposomes, including populations of extracellular vesicles (EV), exosomes and to fusion proteins.


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