The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2025

Filed:

Jun. 02, 2020
Applicant:

Generoath Co., Ltd, Seoul, KR;

Inventors:

Jin Woo Choi, Seoul, KR;

Dong Uk Lee, Seoul, KR;

Ki Hwan Eum, Ansan-si, KR;

Assignee:

Generoath Co., Ltd., Seoul, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
A61K 48/005 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C12N 15/85 (2013.01); C12N 2750/14141 (2013.01);
Abstract

Provided is a pharmaceutical composition for preventing or treating neuronal diseases comprising, as an active ingredient, an exon 2-deleted AIMP2 variant (AIMP2-DX2) gene or a vector comprising the gene, and a method for treating neuronal diseases in animals other than humans, comprising administering the same to a subject in need of treatment. The pharmaceutical composition comprising, as an active ingredient, a AIMP2-DX2 gene or a vector comprising the gene has the effects of apoptosis inhibition, dyskinesia amelioration and oxidative stress inhibition and thus can be widely used for preventing and treating neuronal diseases such as Parkinson's disease and amyotrophic lateral sclerosis.


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