The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2025
Filed:
Mar. 29, 2023
Applicant:
South Dakota Board of Regents, Pierre, SD (US);
Inventors:
Khosrow Rezvani, Vermillion, SD (US);
Grigoriy Sereda, Vermillion, SD (US);
Assignee:
South Dakota Board of Regents, Pierre, SD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/60 (2017.01); A61K 9/51 (2006.01); A61K 31/435 (2006.01); A61K 47/64 (2017.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/60 (2017.08); A61K 9/5115 (2013.01); A61K 9/5161 (2013.01); A61K 9/5169 (2013.01); A61K 31/435 (2013.01); A61K 47/64 (2017.08); A61K 47/645 (2017.08); A61P 35/00 (2018.01);
Abstract
Disclosed herein are compositions for treating cancer comprising a modified veratridine. In certain aspects, the modified veratridine comprises a polyglutamic acid (PLE) or polyethylene glycol/polyglutamic acid (PEG-PLE) conjugated to the 4′ hemiketal thereof. Further disclosed is a method of treating colorectal cancer in a subject comprising administering to a subject an effective amount of the disclosed compositions.