The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2025

Filed:

Apr. 10, 2023
Applicant:

Io Biotech Aps, Copenhagen, DK;

Inventors:

Mads Hald Andersen, Naerum, DK;

Per Thor Straten, Hvidovre, DK;

Assignee:

IO Biotech ApS, Copenhagen, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 38/19 (2006.01); A61K 39/00 (2006.01); A61K 45/06 (2006.01); C12N 9/02 (2006.01);
U.S. Cl.
CPC ...
A61K 38/2013 (2013.01); A61K 38/193 (2013.01); A61K 39/001154 (2018.08); A61K 45/06 (2013.01); C12N 9/0069 (2013.01); C12Y 113/11052 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/572 (2013.01);
Abstract

The invention relates to the field of prophylaxis and therapy of cancer. Provided is a Indoleamine 2,3-dioxygenase (IDO) or peptide fragments hereof that are capable of eliciting anti-cancer immune responses. Specifically, the invention relates to the use of IDO or peptides derived herefrom or IDO specific T-cells for treatment of cancer. The invention thus relates to an anti-cancer vaccine which optionally may be used in combination with other immunotherapies and to IDO specific T-cells adoptively transferred or induced in vivo by vaccination as a treatment of cancer. The invention also provides that the medicaments herein provided may be used in combination with cancer chemotherapy treatment. The invention further provides the prophylaxis and therapy of infections by the same means as described above. The use of IDO and immunogenic peptide fragments hereof in cancer and infection treatment, diagnosis and prognosis is also provided.


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