The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2025
Filed:
Nov. 29, 2018
Applicant:
Spinalcyte Llc, Houston, TX (US);
Inventors:
Pete O'Heeron, Houston, TX (US);
Thomas Ichim, San Diego, CA (US);
Assignee:
Spinalcyte, LLC, Houston, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/33 (2015.01); A61K 35/17 (2015.01); A61K 38/18 (2006.01); A61K 38/20 (2006.01); A61K 38/21 (2006.01); A61K 45/06 (2006.01); A61P 21/00 (2006.01); A61P 37/06 (2006.01); C12N 5/0783 (2010.01); C12N 5/0786 (2010.01);
U.S. Cl.
CPC ...
A61K 35/33 (2013.01); A61K 35/17 (2013.01); A61K 38/1825 (2013.01); A61K 38/1841 (2013.01); A61K 38/1866 (2013.01); A61K 38/20 (2013.01); A61K 38/21 (2013.01); A61K 45/06 (2013.01); A61P 21/00 (2018.01); A61P 37/06 (2018.01); C12N 5/0637 (2013.01); C12N 5/0645 (2013.01);
Abstract
The present disclosure is directed to systems, methods, and compositions for functional interaction of fibroblasts with one or more types of immune cells such that the interaction results in modification to the fibroblasts, the one or more types of immune cells, or both. In some embodiments, one or more certain agents are also utilized during the interaction or in lieu of one of the types of cells. In specific embodiments, cells to be used in cellular transplantation therapy are modified to have reduced immunogenicity.