The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2025

Filed:

Aug. 23, 2022
Applicant:

Alexion Pharmaceuticals, Inc., Boston, MA (US);

Inventors:

Carl Bjartmar, Stockholm, SE;

Karl-Heinz Weiss, Stockholm, SE;

Michael Schilsky, Stockholm, SE;

Frederick Askari, Stockholm, SE;

Anna Czlonkowska, Stockholm, SE;

Peter Ferenci, Stockholm, SE;

Peter Hedera, Stockholm, SE;

Aftab Ala, Stockholm, SE;

Assignee:

Alexion Pharmaceutical, Inc., Boston, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/24 (2019.01); A61K 9/00 (2006.01); A61K 9/28 (2006.01); A61K 31/14 (2006.01); A61P 3/00 (2006.01);
U.S. Cl.
CPC ...
A61K 33/24 (2013.01); A61K 9/0053 (2013.01); A61K 9/28 (2013.01); A61K 31/14 (2013.01); A61P 3/00 (2018.01);
Abstract

Methods for treating Wilson Disease with bis-choline tetrathiomolybdate therapy are provided. The methods may include administering 15 mg or between 30 and 90 mg of bis-choline tetrathiomolybdate once daily to a patient exhibiting NCC, alanine aminotransferase (ALT), hemoglobin, platelets, or neutrophils levels meeting specified criteria. The methods may include modifying treatment by decreasing or increasing the daily dose of bis-choline tetrathiomolybdate or discontinuing treatment for a period of time.


Find Patent Forward Citations

Loading…