The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2025
Filed:
Nov. 10, 2021
Modernatx, Inc., Cambridge, MA (US);
Stephen Hoge, Brookline, MA (US);
William Issa, Dedham, MA (US);
Edward J. Miracco, Arlington, MA (US);
Jennifer Nelson, Brookline, MA (US);
Amy E. Rabideau, Waltham, MA (US);
Gabor Butora, Martinsville, NJ (US);
ModernaTX, Inc., Cambridge, MA (US);
Abstract
The invention relates to improved RNA compositions for use in therapeutic applications. The RNA compositions are particularly suited for use in human therapeutic application (e.g., in RNA therapeutics). The RNA compositions are made by inproved processes, in particular, improved in vitro-transcription (IVT) processes. The invention also relates to methods for producing and purifying RNA (e.g, therapeutic RNAs), as well as methods for using the RNA compositions and therapeutic applications thereof.