The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2025
Filed:
Jan. 06, 2017
Applicants:
The Institute of Cancer Research: Royal Cancer Hospital, London, GB;
Breast Cancer Now, London, GB;
Inventors:
Assignees:
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL, London, GB;
BREAST CANCER NOW, London, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4965 (2006.01); A61K 31/497 (2006.01); A61K 31/506 (2006.01); A61K 31/519 (2006.01); A61K 31/7105 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/497 (2013.01); A61K 31/4965 (2013.01); A61K 31/519 (2013.01); A61K 31/7105 (2013.01); A61P 35/00 (2018.01);
Abstract
The present invention relates to Ataxia-Telangiectasia Mutated and Rad3-related protein kinase (ATR) inhibitors for use in methods of treating BAF-complex deficient cancer. The present invention further provides methods for identifying ATR inhibitors for use in the treatment of BAF complex gene mutant or deficient cancers. Medical uses and methods relating to the treatment of synovial sarcoma using ATR inhibitors are also provided.