The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2025
Filed:
Aug. 21, 2023
Applicant:
H. Lee Moffitt Cancer Center and Research Institute, Inc., Tampa, FL (US);
Inventors:
Pearlie Burnette, Tampa, FL (US);
Nicholas J. Lawrence, Tampa, FL (US);
Harshani Lawrence, Tampa, FL (US);
Assignee:
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC., Tampa, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); A61K 31/4015 (2006.01); A61K 31/427 (2006.01); A61K 31/45 (2006.01); A61K 31/517 (2006.01); A61K 31/551 (2006.01); A61K 47/54 (2017.01); A61K 47/55 (2017.01);
U.S. Cl.
CPC ...
A61K 31/454 (2013.01); A61K 31/4015 (2013.01); A61K 31/427 (2013.01); A61K 31/45 (2013.01); A61K 31/517 (2013.01); A61K 31/551 (2013.01); A61K 47/54 (2017.08); A61K 47/545 (2017.08); A61K 47/55 (2017.08);
Abstract
Disclosed are small molecules against cereblon to enhance effector T cell function. Methods of making these molecules and methods of using them to treat various disease states are also disclosed.