The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2025
Filed:
Jun. 07, 2019
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Brian Kaspar, New Albany, OH (US);
Allan Kaspar, Carlsbad, CA (US);
Kevin Foust, Poway, CA (US);
Martin Fugere, San Diego, CA (US);
Eunhye Park, San Diego, CA (US);
Gretchen Thomsen, San Diego, CA (US);
Fengrong Zuo, San Diego, CA (US);
Assignee:
Novartis AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/569 (2006.01); A61K 48/00 (2006.01); C12N 5/0793 (2010.01); C12N 15/52 (2006.01); C12N 15/63 (2006.01); C12N 15/86 (2006.01); C12N 15/87 (2006.01); G01N 1/30 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56966 (2013.01); A61K 48/005 (2013.01); C12N 5/0619 (2013.01); C12N 15/52 (2013.01); C12N 15/63 (2013.01); C12N 15/86 (2013.01); C12N 15/87 (2013.01); G01N 1/30 (2013.01); A61K 48/00 (2013.01); C12N 2501/11 (2013.01); C12N 2501/115 (2013.01); C12N 2750/14143 (2013.01);
Abstract
The invention relates to an in vitro quantative cell-based assay that uses a primary mouse cell model system permissive to viral vector infection and a quantitative high content image-based system for determining potency of a transgene-expressing viral vector drug product for lot disposition.