The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2025

Filed:

Nov. 22, 2023
Applicant:

Provincial Health Services Authority, Vancouver, CA;

Inventors:

Peter Lansdorp, Vancouver, CA;

Kasmintan Schrader, Vancouver, CA;

Steven Jones, Vancouver, CA;

Vincent Hanlon, Vancouver, CA;

Vahid Akbari, Vancouver, CA;

Kieran O'Neill, Vancouver, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6809 (2018.01); C12Q 1/6883 (2018.01); G16B 20/20 (2019.01); G16B 30/10 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6809 (2013.01); C12Q 1/6883 (2013.01); G16B 20/20 (2019.02); G16B 30/10 (2019.02); C12Q 2600/154 (2013.01); C12Q 2600/156 (2013.01);
Abstract

A method of assigning parent-of-origin to a haplotype, a sub-haplotype or an allele associated with a haplotype. Chromosome-length haplotypes of a genome are generated and a differential methylation status of at least one imprinted differentially methylated region (iDMR) associated with each one of the autosomal chromosomes is determined. The differential methylation status of the at least one iDMR is used to assign parent-of-origin for each one of the chromosome-length haplotypes.


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