The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2025
Filed:
May. 22, 2018
Applicant:
The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);
Inventors:
Andrew P. Magyar, Arlington, MA (US);
Peter Cavanagh, Stanford, CA (US);
Miles Rogers, Cambridge, MA (US);
Kirsty A. McFarland, Melrose, MA (US);
Melissa M. Sprachman, Somerville, MA (US);
Amanda Nicole Billings-Siuti, Framingham, MA (US);
Nicole E. Raustad, Charlestown, MA (US);
Assignee:
The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 (2006.01); C07C 245/08 (2006.01); C07C 247/04 (2006.01); C12P 19/34 (2006.01); C12Q 1/68 (2018.01);
U.S. Cl.
CPC ...
C12N 9/1264 (2013.01); C07C 245/08 (2013.01); C07C 247/04 (2013.01); C12P 19/34 (2013.01); C12Q 1/68 (2013.01); C12Y 207/07031 (2013.01);
Abstract
Described herein are genetically engineered template-independent DNA polymerases, specifically terminal deoxynucleotidyl transferases, and methods of using these polymerases to control DNA synthesis by adding a single nucleotide (mononucleotide) at a time to the 3' end of a growing single-stranded DNA polynucleotide.