The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2025
Filed:
May. 21, 2019
Applicant:
Dsm Ip Assets B.v., Heerlen, NL;
Inventors:
Christopher Mark Farrell, Columbia, MD (US);
Lisa Ann Laprade, Columbia, MD (US);
Otto Martin Lehmann, Kaiseraugst, CH;
Joshua Trueheart, Columbia, MD (US);
Assignee:
DSM IP ASSETS B.V., Heerlen, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/10 (2006.01); C12P 33/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1029 (2013.01); C12P 33/00 (2013.01); C12Y 203/01026 (2013.01);
Abstract
The present invention is related to modified sterol acyltransferase enzymes with improved activity and/or specificity towards acylation of the vitamin D3 precursor 7-dehydrocholesterol (7-DHC) to be used in biotechnological production of vitamin D3. The invention further relates to a yeast strain expressing said modified enzymes and their use in a process for production of vitamin D3 or derivatives and/or metabolites thereof.