The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2025
Filed:
Jul. 23, 2021
Applicant:
Baylor College of Medicine, Houston, TX (US);
Inventors:
Ann Marie Leen, Houston, TX (US);
Juan Fernando Vera Valdes, Bellaire, TX (US);
Cliona M. Rooney, Houston, TX (US);
Ulrike Gerdemann, Cambridge, MA (US);
Assignee:
Baylor College of Medicine, Houston, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61K 39/00 (2006.01); A61K 39/12 (2006.01); C07K 14/025 (2006.01); C07K 14/03 (2006.01); C07K 14/11 (2006.01); C07K 14/135 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0638 (2013.01); A61K 39/12 (2013.01); A61K 39/4611 (2023.05); A61K 39/464838 (2023.05); C07K 14/025 (2013.01); C07K 14/03 (2013.01); C07K 14/11 (2013.01); C07K 14/135 (2013.01); C12N 7/00 (2013.01); A61K 2039/55527 (2013.01); A61K 2039/57 (2013.01); A61K 2039/572 (2013.01); A61K 2039/577 (2013.01); A61K 2039/70 (2013.01); C12N 2501/2302 (2013.01); C12N 2501/2304 (2013.01); C12N 2501/2307 (2013.01); C12N 2501/2315 (2013.01); C12N 2710/16134 (2013.01); C12N 2710/16234 (2013.01); Y02A 50/30 (2018.01);
Abstract
The present invention concerns methods of generating CTLs that are able to target at least one antigen from two or more viruses. The method includes exposing mixtures of peptides for different antigens to the same plurality of PBMCs and, at least in certain aspects, expanding the cells in the presence of IL4 and IL7.