The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2025
Filed:
Apr. 17, 2019
Applicant:
Ucl Business Ltd, London, GB;
Inventors:
Assignee:
UCL Business Ltd, London, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61K 39/00 (2006.01); C07K 14/725 (2006.01); C07K 14/74 (2006.01); C12N 5/0783 (2010.01); C12N 15/87 (2006.01); A61K 35/12 (2015.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/87 (2013.01); A61K 35/17 (2013.01); A61K 39/4611 (2023.05); A61K 39/4621 (2023.05); A61K 39/4632 (2023.05); A61K 39/46433 (2023.05); C07K 14/7051 (2013.01); C07K 14/70539 (2013.01); C12N 5/0637 (2013.01); A61K 2035/122 (2013.01); A61K 38/00 (2013.01); C12N 2510/00 (2013.01);
Abstract
The present invention relates to an engineered regulatory T cell (Treg) comprising a T cell receptor (TCR) which is capable of specifically binding to a myelin basic protein (MBP) peptide or variant or fragment thereof when the peptide is presented by a major histocompatibility complex (MHC) molecule. The present invention further relates to methods for providing an engineered Treg and to methods and uses of said engineered Treg and vectors and kits of vectors encoding said Treg.