The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2025
Filed:
Feb. 08, 2023
Applicant:
City of Hope, Duarte, CA (US);
Inventors:
Marcin Tomasz Kortylewski, Monrovia, CA (US);
Piotr Marek Swiderski, San Dimas, CA (US);
Guido Marcucci, Azusa, CA (US);
Bin Zhang, Duarte, CA (US);
Ya-Huei Kuo, Duarte, CA (US);
Assignee:
City of Hope, Duarte, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); A61K 31/506 (2006.01); A61K 31/7004 (2006.01); A61K 31/704 (2006.01); A61K 31/7125 (2006.01); A61K 45/06 (2006.01); A61K 47/54 (2017.01); A61P 35/02 (2006.01); C07H 21/04 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/506 (2013.01); A61K 31/7004 (2013.01); A61K 31/704 (2013.01); A61K 31/7125 (2013.01); A61K 45/06 (2013.01); A61K 47/549 (2017.08); A61P 35/02 (2018.01); C12N 15/111 (2013.01); C12N 2310/113 (2013.01); C12N 2310/141 (2013.01); C12N 2310/17 (2013.01); C12N 2310/315 (2013.01); C12N 2310/3519 (2013.01);
Abstract
The present disclosure relates to a compound including a nucleic acid sequence conjugated to an anti-microRNA or a microRNA-mimic or a compound including a modified anti-microRNA sequence, compositions of such a compound, and method of treatment of a disease, and method of suppressing microRNA activity by the disclosed compound or composition.