The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2025
Filed:
May. 25, 2018
Applicant:
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Inventors:
Jordan Jarjour, Seattle, WA (US);
Kyle Havens, Seattle, WA (US);
Anne-Rachel Krostag, Lake Forest Park, WA (US);
Assignee:
REGENERON PHARMACEUTICALS, INC., Tarrytown, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); C12N 5/078 (2010.01); C12N 5/0783 (2010.01); C12N 9/10 (2006.01); C12N 15/10 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 15/102 (2013.01); A61K 39/4611 (2023.05); A61K 39/4631 (2023.05); A61K 39/464404 (2023.05); A61P 35/00 (2018.01); C07K 16/2863 (2013.01); C12N 5/0634 (2013.01); C12N 5/0636 (2013.01); C12N 5/0646 (2013.01); C12N 9/10 (2013.01); C12N 9/22 (2013.01); C12N 15/907 (2013.01); A61K 2239/38 (2023.05); C07K 2319/80 (2013.01); C07K 2319/81 (2013.01); C12N 2510/00 (2013.01); C12N 2800/80 (2013.01);
Abstract
The present disclosure provides improved genome editing compositions and methods for editing a CBLB gene. The disclosure further provides genome edited cells for the prevention, treatment, or amelioration of at least one symptom of, a cancer, an infectious disease, an autoimmune disease, an inflammatory disease, or an immunodeficiency.