The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2025
Filed:
Jan. 22, 2019
The Johns Hopkins University, Baltimore, MD (US);
Angelo Cangialosi, Baltimore, MD (US);
ChangKyu Yoon, Timonium, MD (US);
Joshua Fern, Baltimore, MD (US);
Thao D. Nguyen, Baltimore, MD (US);
David H. Gracias, Baltimore, MD (US);
Rebecca Schulman, Baltimore, MD (US);
THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);
Abstract
The present disclosure provides compositions and methods including modular material controllers that combine amplification with logic, translation of input signals, and response tuning to directly and precisely program dramatic material size changes. In particular, the present disclosure provides locked gels having a polymer with a nucleic acid cross link and a nucleic acid lock in a locked conformation preventing the locked gel from reacting with other nucleic acid sequences and methods of unlocking the locked gels by adding a nucleic acid key to the locked gel or by changing an inactive nucleic acid key into an active nucleic acid key with a trigger.