The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2025

Filed:

Jul. 10, 2019
Applicant:

Shenzhen Pregene Biopharma Co. Ltd., Shenzhen, CN;

Inventors:

Jishuai Zhang, Shenzhen, CN;

Hongjian Li, Shenzhen, CN;

Chaolemeng Bao, Shenzhen, CN;

Qinghua Cai, Shenzhen, CN;

Yingying Li, Shenzhen, CN;

Zongpei Song, Shenzhen, CN;

Yijin Ding, Shenzhen, CN;

Zhibo Cai, Shenzhen, CN;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); A61K 39/4611 (2023.05); A61K 39/4631 (2023.05); A61K 39/464417 (2023.05); A61P 35/00 (2018.01); C12N 5/0636 (2013.01); C12N 5/0638 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C07K 2317/76 (2013.01); C07K 2319/33 (2013.01);
Abstract

A group of anti-BCMA single domain antibodies, as well as genes of the single domain antibodies in the group, a vector containing the single domain antibodies in the group, a chimeric antigen receptor, and a T cell modified by a chimeric antigen receptor, and detection and treatment application of the single domain antibodies in the group. The anti-BCMA single domain antibodies have high activity, high stability, high specificity, and high binding capability.


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