The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2025

Filed:

Oct. 23, 2023
Applicants:

Singapore Health Services Pte Ltd, Singapore, SG;

Agency for Science, Technology and Research, Singapore, SG;

Inventors:

Hau Wan Leung, Singapore, SG;

Andre Boon Hwa Choo, Singapore, SG;

Mei Yee Vanessa Ding, Singapore, SG;

Shao Weng Daniel Tan, Singapore, SG;

Narayanan Gopalakrishna Iyer, Singapore, SG;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61K 47/64 (2017.01); A61K 47/68 (2017.01); A61K 51/10 (2006.01); A61P 35/00 (2006.01); C07K 16/30 (2006.01); C07K 16/44 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 47/6415 (2017.08); A61K 47/68031 (2023.08); A61K 47/6857 (2017.08); A61K 51/1048 (2013.01); A61P 35/00 (2018.01); C07K 16/30 (2013.01); C07K 16/44 (2013.01); G01N 33/57473 (2013.01); A61K 2039/505 (2013.01); A61K 2039/55 (2013.01); C07K 2317/732 (2013.01);
Abstract

The present invention relates to an antigen-binding protein, or an antigen-binding fragment thereof which binding to CEACAM6, comprising (i) a heavy chain variable domain comprising a VHCDR1 having the amino acid sequence GNTFTSYVMH; a VHCDR2 having the amino acid sequence YINPYNDGTKYNEKFKG; and a VHCDR3 having the amino acid sequence STARATPYFYAMDY and (ii) a light chain variable domain comprising a VLCDR1 having the amino acid sequence KSSQSLLWSVNQNSYLS, a VLCDR2 having the amino acid sequence GASIRES, and a VLCDR3 having the amino acid sequence QHNHGSFLPYT. The present invention also relates to compositions comprising the antigen-binding protein, or antigen-binding fragment thereof, methods of use of the antigen-binding protein, or antigen-binding fragment thereof for cancer treatment, prevention or detection and a kit comprising the antigen-binding protein, or antigen-binding fragment thereof.


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