The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2025

Filed:

Dec. 02, 2019
Applicant:

Teijin Pharma Limited, Tokyo, JP;

Inventors:

Akira Tanokura, Tokyo, JP;

Hirotsugu Kato, Tokyo, JP;

Hiroshi Eguchi, Tokyo, JP;

Kenichiro Takagi, Tokyo, JP;

Satoshi Yamamura, Tokyo, JP;

Naoko Namiki, Tokyo, JP;

Daisuke Ishikawa, Kikuchi, JP;

Hirofumi Higuchi, Kikuchi, JP;

Tomoyo Takeo, Kikuchi, JP;

Masayo Ohori, Kikuchi, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61P 3/10 (2006.01); C07K 16/22 (2006.01); C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61P 3/10 (2018.01); C12N 5/0658 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01);
Abstract

Provided is a humanized antibody that, through IGF-I receptor, increases muscle mass but does not lower the blood glucose level. This humanized antibody: is an anti-IGF-I receptor humanized antibody, a fragment thereof, or a derivative thereof; has a specific amino acid sequence such as SEQ ID NOs: 1 to 6 serving as a CDR sequence; and specifically binds to IGF-I receptor extracellular domain.


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