The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2025
Filed:
Mar. 21, 2023
Applicants:
University of Washington, Seattle, WA (US);
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Inventors:
Daniel Adriano Silva Manzano, Seattle, WA (US);
Shawn Yu, Seattle, WA (US);
Umut Ulge, Seattle, WA (US);
David Baker, Seattle, WA (US);
Kenan Christopher Garcia, Seattle, WA (US);
Jamie Spangler, Seattle, WA (US);
Carl Walkey, Seattle, WA (US);
Assignees:
UNIVERSITY OF WASHINGTON, Seattle, WA (US);
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, Stanford, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/55 (2006.01); A61K 38/00 (2006.01); A61K 47/60 (2017.01); A61K 47/62 (2017.01); C07K 14/54 (2006.01);
U.S. Cl.
CPC ...
C07K 14/55 (2013.01); A61K 47/60 (2017.08); A61K 47/62 (2017.08); C07K 14/5406 (2013.01); C07K 14/5437 (2013.01); C07K 14/5443 (2013.01); A61K 38/00 (2013.01); C07B 2200/13 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01); C07K 2319/74 (2013.01);
Abstract
De novo designed polypeptides that bind to IL-2 receptor βγheterodimer (IL-2Rβγ), IL-4 receptor αγheterodimer (IL-4Rαγ), or IL-13 receptor α subunit (IL-13Rα) are disclosed, as are methods for using and designing the polypeptides.