The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2025

Filed:

Jul. 10, 2019
Applicant:

Biophore India Pharmaceuticals Pvt. Ltd, Hyderabad, IN;

Inventors:

Manik Reddy Pullagurla, Hyderabad, IN;

Jagadeesh Babu Rangisetty, Hyderabad, IN;

Bhaskar Reddy Pitta, Hyderabad, IN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 5/00 (2006.01); C07B 63/04 (2006.01); C07F 3/00 (2006.01);
U.S. Cl.
CPC ...
C07F 5/003 (2013.01); C07B 63/04 (2013.01); C07F 3/003 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention relates to an improved process for the preparation of 2,2′,2″-(10-((2R,3S)-1,3,4-trihydroxy butan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl) triacetic acid, gadolinium (III) with iron metal content less than 5 ppm and free gadolinium content less than 10 ppm, which is represented by the formula (1). The present invention further relates to an improved process for the preparation of calcium complex of 10-(2,3-Dihydroxy-1-(hydroxymethyl)propyl)-1,4,7,10-tetraazacyclo decane-1,4,7-triacetic acid known as Calcobutrol (1a) and its sodium salt of formula (1b) with purity greater than 98.0%.


Find Patent Forward Citations

Pullagurla, Manik. (2025). Process for the preparation of 2,2',2″-(10-((2r,3s)-1,3,4-trihydroxy butan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl) triacetic acid and its complexes (U.S. Patent No. 12227527). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12227527

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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