The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2025
Filed:
Feb. 28, 2020
Applicant:
Celgene Corporation, Summit, NJ (US);
Inventors:
John Fitzgerald Traverse, Lebonon, NJ (US);
Nareshkumar Jain, Flemington, NJ (US);
Srinath Thirumalairajan, Bensalem, PA (US);
Sanjeevani Ghone, Plainsboro, NJ (US);
Assignee:
CELGENE CORPORATION, Summit, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/18 (2006.01);
U.S. Cl.
CPC ...
C07D 498/18 (2013.01);
Abstract
A scaled process of preparing maytansinol, FORMULA II, is provided by reacting a compound of Formula I, wherein R is selected from the group consisting essentially of alkyl, branched alkyl, aryl, alkenyl, alkynyl, as well as substituted variations thereof, with at least one organometallic reagent to produce the compound of Formula II; and, isolating the compound of Formula II.