The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2025

Filed:

Sep. 21, 2023
Applicant:

King Faisal University, Al-Ahsa, SA;

Inventors:

Katharigatta N. Venugopala, Al-Ahsa, SA;

Pran Kishore Deb, Ranchi, IN;

Raghu Prasad Mailavaram, Dhule, IN;

Nizar A. Al-Shar'i, Irbid, JO;

Swastika Ganguly, Ranchi, IN;

Bapi Gorain, Ranchi, IN;

Annie Lee Pei Wen, Kuala Lumpur, MY;

Goh Hui Shan, Kuala Lumpur, MY;

Assignee:

KING FAISAL UNIVERSITY, Al-Ahsa, SA;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01);
Abstract

Novel 2-(substituted benzyl)-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-ones and 4-fluoro-N-(4-oxo-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)benzamide compounds, a method of synthesizing said compounds, a pharmaceutical composition comprising said compounds and a suitable carrier, and a method of using the compounds. The 2-(substituted benzyl)-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-ones and 4-fluoro-N-(4-oxo-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)benzamide compounds, identified as COX-2 inhibitors, are useful as anti-inflammatory and pain agents.


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