The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2025
Filed:
May. 08, 2023
Applicant:
Agency for Science, Technology and Research, Singapore, SG;
Inventor:
Vikrant Arun Adsool, Singapore, SG;
Assignee:
Agency for Science, Technology and Research, Singapore, SG;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/08 (2006.01); C07D 215/233 (2006.01); C07D 401/12 (2006.01); C07D 451/06 (2006.01); C07D 451/14 (2006.01);
U.S. Cl.
CPC ...
C07D 491/08 (2013.01); C07D 215/233 (2013.01); C07D 401/12 (2013.01); C07D 451/06 (2013.01); C07D 451/14 (2013.01);
Abstract
The present disclosure relates to derivatives of bicyclic compounds and their uses in therapy. In particular, the present disclosure relates to derivatives of bicyclic compounds for use in modulating kinase enzymatic activity and accordingly modulating kinase-dependent diseases and conditions such as cancer and in specific embodiments, hepatocellular carcinoma (HCC). The present disclosure also relates to methods of synthesizing these compounds.