The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2025
Filed:
May. 16, 2022
Applicant:
Florida A&m University, Tallahassee, FL (US);
Inventors:
Edward Agyare, Tallahassee, FL (US);
Xue You Zhu, Tallahassee, FL (US);
Andriana Inkoom, Tallahassee, FL (US);
Nkafu Bechem Ndemazie, Tallahassee, FL (US);
Assignee:
Florida A&M University, Tallahassee, FL (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/04 (2006.01); A61K 31/513 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 405/04 (2013.01); A61K 31/513 (2013.01); A61P 35/00 (2018.01);
Abstract
Novel compounds and methods of using the compounds and compositions to treat pancreatic cancer are presented. Novel compounds N-(5-fluoro-2-oxo-1-(tetrahydrofuran-2-yl)-1,2-dihydropyrimidin-4-yl)octanamide and N-(5-fluoro-2-oxo-1-(tetrahydrofuran-2-yl)-1,2-dihydropyrimidin-4-yl)dodecanamide are provided. The compounds have been shown to induce cytotoxicity in pancreatic cancer cells and can serve as a novel oral treatment for pancreatic cancer.