The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2025

Filed:

Feb. 22, 2023
Applicant:

Orthocell Limited, Murdoch, AU;

Inventor:

Ming Hao Zheng, City Beach, AU;

Assignee:

Orthocell Ltd., Murdoch, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/24 (2006.01); A61L 27/36 (2006.01); A61L 27/56 (2006.01); A61L 27/58 (2006.01); C07K 1/113 (2006.01); C07K 14/78 (2006.01); A61F 2/18 (2006.01);
U.S. Cl.
CPC ...
A61L 27/24 (2013.01); A61L 27/3604 (2013.01); A61L 27/3683 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); C07K 1/1136 (2013.01); C07K 14/78 (2013.01); A61F 2002/183 (2013.01); A61L 2430/14 (2013.01); A61L 2430/40 (2013.01);
Abstract

The present invention relates to a method of producing a collagen membrane that has particular mechanical properties. In particular, the present invention relates to a method A of producing a collagen membrane comprising the steps of (i) isolating a collagen-containing tissue and incubating same in an ethanol solution; (ii) incubating the collagen-containing tissue from step (i) in a first solution comprising an inorganic salt and an anionic surfactant in order to denature non-collagenous proteins contained therein; (iii) incubating the collagen-containing tissue produced in step (ii) in a second solution comprising an inorganic acid until the collagen in said material is denatured; and (iv) incubating the collagen-containing tissue produced in step (iii) in a third solution comprising an inorganic acid with simultaneous mechanical stimulation for sufficient time to enable the collagen bundles in said collagen-containing tissue to align; wherein the mechanical stimulation comprises applying tension cyclically to the collagen-containing tissue.


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