The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2025

Filed:

Nov. 15, 2019
Applicant:

Arcus Biosciences, Inc., Hayward, CA (US);

Inventors:

Joel Beatty, San Mateo, CA (US);

Eric Thomas Newcomb, Menlo Park, CA (US);

Jay Patrick Powers, Pacifica, CA (US);

Brandon Reid Rosen, San Mateo, CA (US);

Yongli Su, Foster City, CA (US);

Anh Thu Tran, Union City, CA (US);

Corinne Nicole Foley, San Carlos, CA (US);

Rebecca Louise Grange, Union City, CA (US);

Tezcan Guney, Hayward, CA (US);

Steven Donald Jacob, Oakland, CA (US);

Jaroslaw Kalisiak, Mountain View, CA (US);

Manmohan Reddy Leleti, Dublin, CA (US);

Erick Allen Lindsey, Fremont, CA (US);

Debashis Mandal, Fremont, CA (US);

Assignee:

Arcus Biosciences, Inc., Hayward, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/69 (2006.01); A61K 31/282 (2006.01); A61K 31/704 (2006.01); A61K 33/243 (2019.01); A61K 39/395 (2006.01); C07F 5/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/69 (2013.01); A61K 31/282 (2013.01); A61K 31/704 (2013.01); A61K 33/243 (2019.01); A61K 39/3955 (2013.01); C07F 5/025 (2013.01);
Abstract

Compounds that are inhibitors of at least one of ARG1 and ARG2, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by ARG1 and ARG2 are also described herein.


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