The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2025

Filed:

Dec. 15, 2017
Applicant:

Spero Therapeutics, Inc., Cambridge, MA (US);

Inventors:

Akash Jain, Cambridge, MA (US);

Enxian Lu, Shanghai, CN;

Shaoqiong Lyu, Shanghai, CN;

Shoufeng Li, North Brunswick, NJ (US);

Timothy Keutzer, Cambridge, MA (US);

Luke Utley, Cambridge, MA (US);

Grazyna Fraczkiewicz, Lancaster, CA (US);

Joyce MacWan, Lancaster, CA (US);

Assignee:

SPERO THERAPEUTICS, INC., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 9/28 (2006.01); A61K 31/427 (2006.01);
U.S. Cl.
CPC ...
A61K 31/427 (2013.01); A61K 9/0053 (2013.01); A61K 9/2013 (2013.01); A61K 9/2018 (2013.01); A61K 9/2027 (2013.01); A61K 9/2054 (2013.01); A61K 9/2059 (2013.01); A61K 9/2846 (2013.01);
Abstract

Immediate and modified release oral dosage forms of tebipenem pivoxil including dosage form cores are provided. The dosage form core includes tebipenem pivoxil in free base or salt form, and excipients including a binder, a lubricant, optionally a diluent, and optional additional excipients. The weight to weight ratio of tebipenem pivoxil to the excipients in the dosage form core is from 30:60 to 60:30. The disclosure includes methods of treating bacterial infections including complicated urinary tract infections.


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