The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2025
Filed:
Nov. 21, 2023
Applicant:
Aurigene Oncology Limited, Bangalore, IN;
Inventors:
Pottayil Govindan Nair Sasikumar, Bangalore, IN;
Muralidhara Ramachandra, Bangalore, IN;
Seetharamaiah Setty Sudarshan Naremaddepalli, Bangalore, IN;
Nagaraj Gowda, Bangalore, IN;
Assignee:
Aurigene Oncology Limited, Bangalore, IN;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4245 (2006.01); A61K 31/454 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4245 (2013.01); A61K 31/454 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01);
Abstract
The present disclosure relates to 3-substituted 1,2,4-oxadiazole compounds and their derivatives, which are useful as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3) inhibitors or as dual inhibitors of TIM-3 and the programmed cell death 1 (PD-1) signaling pathway. The disclosure also relates to treatment of disorders by inhibiting an immunosuppressive signal induced by TIM-3, PD-1, PD-L1, and/or PD-L2.