The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2025
Filed:
Jun. 07, 2022
Solentim Ltd., Dorset, GB;
Yonggang Jiang, Dorset, GB;
Advanced Instruments Ltd., Dorset, GB;
Abstract
There is provided a cell analysis apparatus that comprises image capture circuitry for capturing a brightfield image of a cell using brightfield imaging. The cell has been dyed by a functional dye that indicates, during fluorescence imaging and during brightfield imaging, whether the cell has a given characteristic. A model derived by machine learning is stored and used in combination with the brightfield image to determine whether the cell has the given characteristic. There is also provided a method for creating a cell categorisation model, comprising applying a functional dye to one or more samples comprising a plurality of cells. The functional dye indicates during fluorescence imaging and during brightfield imaging whether each of the cells has a given characteristic. A brightfield image and a corresponding fluorescence image for each of the plurality of cells to which the dye has been applied are captured and a machine learning process is used to generate a model that predicts whether a cell has the given characteristic from a brightfield image. The model is generated by using the brightfield image and the corresponding fluorescence image of each of the plurality of cells as training data.