The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2025
Filed:
Dec. 02, 2019
Applicant:
The University of Tokyo, Tokyo, JP;
Inventors:
Assignee:
The University of Tokyo, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/37 (2006.01); C07F 9/655 (2006.01); C07F 9/6561 (2006.01); C09K 11/06 (2006.01); G01N 21/64 (2006.01); G01N 33/542 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/37 (2013.01); C09K 11/06 (2013.01); G01N 21/6428 (2013.01); G01N 33/542 (2013.01); C07F 9/655 (2013.01); C07F 9/6561 (2013.01); G01N 2021/6439 (2013.01); G01N 2333/948 (2013.01);
Abstract
A compound is represented by the following general formula (I): The compound or a salt thereof provides a fluorescent probe for detecting carboxypeptidase activity In the formula, Rrepresents an alkyl group having 1 to 6 carbon atoms or an alkoxy group having 1 to 6 carbon atoms; T represents an amino acid residue or a residue of an amino acid derivative; S represents a C-terminal amino acid residue. represents a fluorophore, and the fluorophore is a fluorophore in which an absorption/fluorescence wavelength greatly changes or a quenched state changes to a fluorescent state by elimination of the —P(═O)(—R)-T-S moiety.