The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2025
Filed:
Aug. 06, 2021
Applicant:
Alteogen Inc., Daejeon, KR;
Inventors:
Soon Jae Park, Daejeon, KR;
Kyuwan Kim, Daejeon, KR;
Sang Hoon Yun, Daejeon, KR;
Jeong Soo Cho, Daejeon, KR;
Kibum Park, Daejeon, KR;
Minsoo Byun, Daejeon, KR;
Hyung-Nam Song, Daejeon, KR;
Ji-Sun Kim, Daejeon, KR;
Ki Seok Nam, Daejeon, KR;
Assignee:
ALTEOGEN Inc., Daejeon, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/26 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2474 (2013.01); C12Y 302/01035 (2013.01);
Abstract
Disclosed is a method for producing hyaluronidase or a variant thereof. Specifically, the method is capable of changing the N-glycan levels under culture conditions including a controlled concentration of glucose in the culture medium and a decreased culture temperature for a specific culture time period, thereby increasing the specific activity by 10% or more and improving the quality and production yield.