The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 11, 2025

Filed:

Aug. 05, 2016
Applicant:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Inventors:

Christian Hinderer, Philadelphia, PA (US);

James M. Wilson, Philadelphia, PA (US);

Matthew Wilson, Philadelphia, PA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61K 38/26 (2006.01); A61K 38/28 (2006.01); A61K 48/00 (2006.01); A61P 3/10 (2006.01); C07K 14/00 (2006.01); C07K 14/605 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 38/26 (2013.01); A61K 38/28 (2013.01); A61K 48/00 (2013.01); A61K 48/005 (2013.01); A61K 48/0058 (2013.01); A61P 3/10 (2018.01); C07K 14/00 (2013.01); C07K 14/605 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14171 (2013.01); C12N 2800/22 (2013.01);
Abstract

Compositions and methods for treating type II diabetes in a subject. A viral vector is provided which includes a nucleic acid molecule comprising a sequence encoding a propeptide and the active portion of GLP-1, wherein, when expressed, the N-terminal amino acid of GLP-1 immediately follows the C-terminal amino acid of the propeptide. In desired embodiments, the subject is a cat or dog.


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