The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 11, 2025

Filed:

Jun. 08, 2019
Applicant:

Lankenau Institute for Medical Research, Wynnewood, PA (US);

Inventors:

Scott K. Dessain, Wynnewood, PA (US);

Rashmi Sharma, King of Prussia, PA (US);

Fetweh H. Al-Saleem, Philadelphia, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C07K 16/28 (2006.01); G01N 33/564 (2006.01);
U.S. Cl.
CPC ...
C07K 16/286 (2013.01); G01N 33/564 (2013.01); G01N 2333/70571 (2013.01); G01N 2800/24 (2013.01);
Abstract

A recombinant, synthetic or monoclonal human antibody or fragment thereof that binds to an N-methyl-D-aspartate Receptor (NMDAR) epitope, which antibody or fragment comprises at least one a heavy chain variable domain sequence encoded by a nucleic acid sequence that is at least 80% identical to SEQ ID NOs. 1, 3, or 5; or at least one a light chain variable domain sequence encoded by a nucleic acid sequence that is at least 80% identical to SEQ ID NOs: 2, 4, or 6. Assays for diagnosis of ANRE employ these NMDAR-binding antibodies, constructs, or epitope binding fragments. In one embodiment, multiple of the NMDAR-binding antibodies or fragments are used as controls because they bind non-overlapping target sequences on the NMDAR ATD.


Find Patent Forward Citations

Quick Actions:

Dessain, Scott. (2025). Anti-nmda receptor antibodies and methods of use (U.S. Patent No. 12221484). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12221484

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…