The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2025
Filed:
Nov. 29, 2017
Cas Lamvac (Guangzhou) Biomedical Technology Co., Ltd., Guangzhou, CN;
Wen Hu, Guangdong, CN;
Yongchao Yao, Guangdong, CN;
Wenzhong Guo, Guangdong, CN;
Yinbo Jiang, Guangdong, CN;
Shuozhou Huang, Guangdong, CN;
Ting Jiang, Guangdong, CN;
Jiaojiao Li, Guangdong, CN;
Zhu Tao, Guangdong, CN;
Yanli Gu, Guangdong, CN;
Huihui Zhang, Guangdong, CN;
Li Qin, Guangdong, CN;
Xiaoping Chen, Guangdong, CN;
CAS Lamvac (Guangzhou) Biomedical Technology Co., Ltd., Guangzhou, CN;
Abstract
Provided are a chimeric antigen receptor and an application thereof; said chimeric antigen receptor contains a domain which identifies any one of, or a combination of at least two of, the malarial protein VAR2CSA, a protein tag on malarial protein VAR2CSA, or a compound capable of labeling the malarial protein VAR2CSA. The chimeric antigen receptor can identify the VAR2CSA protein or the recombinant protein (rVAR2) of any one of, or at least two of, the domains of the VAR2CSA protein which can bind to placental-like chondroitin sulfate A (pl-CSA). The VAR2CSA protein or rVAS2 protein is capable of targeting several different types of tumor cells by means of binding to the pl-CSA on the surface of the tumor cell.