The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2025
Filed:
Jul. 02, 2019
Applicant:
Merck Patent Gmbh, Darmstadt, DE;
Inventors:
Rudolf Moser, Schaffhausen, CH;
Viola Groehn, Dachsen, CH;
Ruth Boehni Stamm, Stein Am Rhein, CH;
Fritz Blatter, Reinach, CH;
Martin Szelagiewicz, Basel, CH;
Assignee:
MERCK PATENT GMBH, Darmstadt, DE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 475/04 (2006.01); A61K 45/06 (2006.01); C07C 229/36 (2006.01);
U.S. Cl.
CPC ...
C07D 475/04 (2013.01); A61K 45/06 (2013.01); C07C 229/36 (2013.01); C07B 2200/13 (2013.01);
Abstract
The present invention refers to a crystalline salt comprising 5-methyl-(6S)-tetrahydrofolic acid and an amino acid ethyl ester like L-phenylalanine ethyl ester or L-methionine ethyl ester, wherein the molar ratio of 5-methyl-(6S)-tetrahydrofolic acid to amino acid ethyl ester is from 1:0.3 to 1:3.0 (in mol/mol) and/or hydrates and/or solvates thereof as well as to a process of obtaining the same.