The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2025
Filed:
Jul. 15, 2020
Applicant:
Virginia Commonwealth University, Richmond, VA (US);
Inventor:
Shijun Zhang, Glen Allen, VA (US);
Assignee:
Virginia Commonwealth University, Richmond, VA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 333/24 (2006.01); A61P 37/02 (2006.01); C07C 311/37 (2006.01); C07C 311/46 (2006.01); C07D 207/20 (2006.01); C07D 209/14 (2006.01); C07D 233/26 (2006.01); C07D 241/12 (2006.01); C07D 249/04 (2006.01); C07D 277/56 (2006.01); C07D 277/593 (2006.01); C07D 285/06 (2006.01); C07D 307/64 (2006.01); C07D 317/62 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07C 311/37 (2013.01); A61P 37/02 (2018.01); C07C 311/46 (2013.01); C07D 207/20 (2013.01); C07D 209/14 (2013.01); C07D 233/26 (2013.01); C07D 241/12 (2013.01); C07D 249/04 (2013.01); C07D 277/56 (2013.01); C07D 277/593 (2013.01); C07D 285/06 (2013.01); C07D 307/64 (2013.01); C07D 317/62 (2013.01); C07D 333/24 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01);
Abstract
Scaffold compounds are used to design small molecule compounds and structure-activity relationship studies identify inhibitors of inflammation. Methods include pharmaceutical compositions of the small molecule compounds to inhibit, prevent and treat diseases and conditions associated with inflammation, including multiple sclerosis, Alzheimer's disease, acute myocardial infarction, traumatic brain injury and autoinflammatory diseases.