The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 11, 2025

Filed:

Mar. 05, 2024
Applicant:

The General Hospital Corporation, Boston, MA (US);

Inventors:

Ravi Kapur, Sharon, MA (US);

Kyle C. Smith, Cambridge, MA (US);

Mehmet Toner, Charlestown, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); A61K 35/28 (2015.01); G01N 1/40 (2006.01); G01N 15/00 (2024.01); G01N 15/01 (2024.01); G01N 15/02 (2024.01); G01N 15/06 (2024.01); G01N 15/14 (2024.01); G01N 15/149 (2024.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); A61K 35/28 (2013.01); B01L 3/502715 (2013.01); B01L 3/502746 (2013.01); B01L 3/502753 (2013.01); G01N 1/4077 (2013.01); G01N 15/0255 (2013.01); G01N 15/0618 (2013.01); G01N 15/1484 (2013.01); B01L 3/502776 (2013.01); B01L 2200/0631 (2013.01); B01L 2200/0647 (2013.01); B01L 2200/0652 (2013.01); B01L 2200/0668 (2013.01); B01L 2200/0684 (2013.01); B01L 2200/12 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0877 (2013.01); B01L 2300/185 (2013.01); B01L 2400/0409 (2013.01); B01L 2400/0415 (2013.01); B01L 2400/043 (2013.01); B01L 2400/0436 (2013.01); B01L 2400/0457 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/082 (2013.01); G01N 2001/4088 (2013.01); G01N 2015/0053 (2013.01); G01N 15/01 (2024.01); G01N 2015/0288 (2013.01); G01N 2015/1486 (2013.01); G01N 15/149 (2024.01); G01N 2015/1493 (2013.01);
Abstract

A microfluidic device includes: a first microfluidic channel; a second microfluidic channel extending along the first microfluidic channel; and a first array of islands separating the first microfluidic channel from the second microfluidic channel, in which each island is separated from an adjacent island in the array by an opening that fluidly couples the first microfluidic channel to the second microfluidic channel, in which the first microfluidic channel, the second microfluidic channel, and the islands are arranged so that a fluidic resistance of the first microfluidic channel increases relative to a fluidic resistance of the second microfluidic channel along a longitudinal direction of the first microfluidic channel such that, during use of the microfluidic device, a portion of a fluid sample flowing through the first microfluidic channel passes through one or more of the openings between adjacent islands into the second microfluidic channel.


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