The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2025
Filed:
Jul. 30, 2019
Applicant:
Daiichi Sankyo Company, Limited, Tokyo, JP;
Inventors:
Kiyoshi Sugihara, Tokyo, JP;
Chiaki Ishii, Tokyo, JP;
Assignee:
DAIICHI SANKYO COMPANY, LIMITED, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61K 31/4745 (2006.01); A61K 47/54 (2017.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6843 (2017.08); A61K 31/4745 (2013.01); A61K 47/545 (2017.08); A61K 47/68037 (2023.08); A61K 47/6849 (2017.08); A61K 47/6851 (2017.08); A61K 47/6855 (2017.08); A61K 47/6889 (2017.08); A61P 35/00 (2018.01); A61P 35/04 (2018.01); C07K 16/18 (2013.01); C07K 16/28 (2013.01); C07K 16/2827 (2013.01); C07K 16/30 (2013.01); C07K 16/32 (2013.01);
Abstract
A therapeutic agent for a metastatic brain tumor comprising, as an active component, an antibody-drug conjugate in which a drug-linker represented by the following formula (wherein A represents a connecting position to an antibody) is conjugated to the antibody via a thioether bond and/or a method of treatment for a metastatic brain tumor, comprising administering the antibody-drug conjugate to a subject in need of the treatment for a metastatic brain tumor.