The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2025
Filed:
Jul. 03, 2024
Applicant:
The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, CN;
Inventors:
Chenghao Jiang, Nanjing, CN;
Fei Jiang, Nanjing, CN;
Bin Yan, Nanjing, CN;
Mingliang Zhou, Shanghai, CN;
Yuhan Peng, Nanjing, CN;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 31/12 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5115 (2013.01); A61K 9/5123 (2013.01); A61K 9/5146 (2013.01); A61K 9/5192 (2013.01); A61K 31/12 (2013.01);
Abstract
Manganese-doped hollow mesoporous silica nanoparticles loaded with curcumin and an application in periodontal bone tissue repair are provided in the present disclosure, belonging to the technical field of targeted delivery of nanoparticles and bone tissue regeneration. In the present disclosure, alendronate is grafted on the surface of silica nanoparticles to achieve bone targeting, manganese is doped on the nanoparticles by a chemical method, and curcumin is wrapped in the nanoparticles.