The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2025
Filed:
Mar. 02, 2019
Applicant:
Saint Joseph's University, Philadelphia, PA (US);
Inventors:
Vaishnavi Parikh, Sellersville, PA (US);
Pardeep Gupta, West Chester, PA (US);
Assignee:
Saint Joseph's University, Philadelphia, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 38/17 (2006.01); A61K 38/27 (2006.01); A61K 47/34 (2017.01);
U.S. Cl.
CPC ...
A61K 9/146 (2013.01); A61K 38/27 (2013.01);
Abstract
The present invention relates to the discovery of novel PLGA particles comprising a polypeptide adsorbed on the surface of the PLGA particles. In certain embodiments, the PLGA particles can be used to administer the polypeptide to a patient in need thereof. As compared to polypeptide-delivery formulations known in the art, the present invention demonstrates a higher relative polypeptide loading capacity. In certain embodiments, the polypeptide adsorbed on the surface of the PLGA nanoparticles does not denature or deform upon adsorption.