The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2025
Filed:
Sep. 01, 2020
Applicant:
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Inventor:
Larry R. Pease, Rochester, MN (US);
Assignee:
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); A61K 35/17 (2015.01); A61K 39/00 (2006.01); C07K 14/74 (2006.01); G01N 33/50 (2006.01); G01N 33/569 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 35/17 (2013.01); A61K 39/0008 (2013.01); A61K 39/001106 (2018.08); A61K 39/00115 (2018.08); A61K 39/001151 (2018.08); A61K 39/001153 (2018.08); A61K 39/001156 (2018.08); A61K 39/001157 (2018.08); A61K 39/001162 (2018.08); A61K 39/00117 (2018.08); A61K 39/001182 (2018.08); A61K 39/001186 (2018.08); A61K 39/001188 (2018.08); A61K 39/001191 (2018.08); A61K 39/001192 (2018.08); A61K 39/001193 (2018.08); A61K 39/001194 (2018.08); A61K 39/001197 (2018.08); A61K 39/4611 (2023.05); A61K 39/4621 (2023.05); A61K 39/46433 (2023.05); C07K 14/70539 (2013.01); C12N 7/00 (2013.01); G01N 33/505 (2013.01); G01N 33/56977 (2013.01); A61K 38/00 (2013.01); A61K 2039/53 (2013.01); A61K 2039/572 (2013.01); C12N 2710/10043 (2013.01); G01N 2333/70539 (2013.01);
Abstract
Materials and methods for identifying and using MHC molecule variants for activating self-reactive T cells in a peptide-specific manner, and their use to focus autoimmune cellular responses against diseases such as cancers and persisting viral infections, are described.